CBD is known for its antioxidative and neuroprotective effects. For these reasons, many people take CBD oil to improve memory. Where exactly does CBD excel at when it comes to our memory functioning? Learn more about CBD and its use for the brain. <strong>Dana Smith: </strong>Legalisation presents an opportunity to promote cannabis rich in a chemical that protects against its negative effects CBD’s unique neurological health benefits could be the reason why some people see it as an appealing alternative remedy to help with memory loss. Learn more.
CBD and Memory: Can Hemp Oil Enhance Memory?
Cannabis users have long been thought of as people with short-term memory problems due to an alleged negative impact of cannabinoids — the active ingredients in cannabis plants — on the brain cells.
Ironically, the infamous THC has been recently shown to have neuroprotective effects on brain cells during studies. This means that cannabis, instead of killing healthy brain cells, protects them against damage. This fairly recent discovery sheds new light on the potential use of cannabinoids in the treatment of memory issues.
And as for CBD, neuroprotection is believed to be one of the compound’s major roles.
So, have we been misinformed all that time?
Apparently yes, but this isn’t the subject of our article.
Today, we’re going to cover CBD’s potential in fighting Cognitive Decline (CD), the scientific term used to diagnose memory loss. The condition is more likely to occur with aging; that’s why learning more about CBD, including its effects on catabolic processes in the brain, is essential to understand how it can help with memory issues.
Does CBD Help with Memory?
In recent years, CBD has been found to alleviate certain symptoms of memory loss conditions, including different types of dementia. People are turning to CBD oil to treat Alzheimer’s disease as well as to improve focus and enhance the daily performance of their brains.
We have all experienced temporary memory glitches, but if memory loss becomes chronic and compromises your daily functioning, it may be time to seek out treatment.
CBD interacts with the master regulatory network known as the endocannabinoid system (ECS). From there, it operates on over 65 molecular pathways, ensuring the balanced functioning of ECS and the maintenance of homeostasis (1). Homeostasis is a biological term describing the harmony between all biological functions in the human body.
The interaction between CBD and the central nervous system (CNS) is where the cannabinoid manifests its benefits for memory.
In the next section, we cover the most common memory issues CBD is known to help with, and back it up with scientific research.
CBD and Memory Issues: The Benefits
Perhaps the most important benefit of CBD for people with memory problems is that the compound is non-intoxicating. Unlike THC, CBD won’t get you high because it doesn’t have a direct affinity to any of the cannabinoid receptors in the brain. CBD can even negate the psychotropic potential of CBD by blocking the sites of these receptors when THC tries to bind to them.
THC can help enhance memory in people with neurodegenerative disorders, but as we said, this article focuses specifically on CBD. And if you’re reading this, you’re probably interested in achieving memory improvements without the psychoactive buzz.
CBD has been established as a potential remedy for people who struggle with a variety of cognitive disorders. However, because the research is in its early stages, more studies in this regard are needed to confirm preclinical findings.
For now, let’s focus on the most important studies investigating the efficacy of CBD for common memory ailments.
CBD for Alzheimer’s and Dementia Memory Loss
Memory loss triggered by degenerative conditions, such as dementia and Alzheimer’s disease, is a significant area that CBD oil has been shown to alleviate inflammation of the brain, reduce oxidative stress, and improve the regeneration of neurons, all of which can help improve cognitive performance.
Patients with Alzheimer’s disease experience progressive cognitive decline due to the degeneration of neurons in the brain, which further destroys neural pathways. Numerous studies have shown that CBD oil not only prevents the destruction of these neurons, but it also aids the body in creating new ones (neurogenesis). (2)
CBD for Memory Loss Caused by Stress and Anxiety
While analyzing the impact of CBD on the brain cells, researchers have discovered that it can actually mitigate brain damage caused by physical trauma and severe stress.
Studies have shown that the body starts to release endocannabinoids (the body’s version of plant-based cannabinoids) to defend the brain and repair it (3). When phytocannabinoids like CBD are administered to the endocannabinoid system, it strengthens the defensive response, therefore strengthening the memory.
Moreover, there is a large body of evidence supporting the use of CBD in the treatment of traumatic brain injury that derives from neuroinflammation (4). Since CBD is such a potent anti-inflammatory compound, it could help you after memory loss caused by an injury that brought inflammation to your brain.
CBD for Memory Loss Due to Lack of Focus
If your memory issues are caused by an inability to focus, CBD oil may come in handy, as shown by studies that tested the efficacy of CBD as a potential treatment for ADHD, including children.
In a review published in the Journal of Pediatric Pharmacology and Therapeutics, the authors reported that CBD oil had been shown to support people with a range of medical conditions, including the behavioral symptoms of ADHD, such as a short attention span (5). Another study mentions anxiolytic (anti-anxiety) and sleep-regulating properties of CBD, both of which contribute to better memory retention (6).
However, it is unclear whether CBD oil can improve your cognitive function if your memory loss doesn’t stem from a diagnosed condition or disease. A comprehensive review of 27 previously conducted studies found that apart from improving the mental health of patients with schizophrenia, CBD oil didn’t have significant effects on memory functioning in otherwise healthy subjects (7).
So, whether the therapeutic effects of CBD on the brain are universal is still up to debate; that’s why we need more longitudinal human trials to draw definitive conclusions on CBD as a memory booster.
CBD, Memory, and Addiction
In addition to the aforementioned publications, an additional study suggests that CBD may be a promising treatment for people recovering from addiction due to its effect on memory (8).
The study introduces the idea of CBD having “a disruptive effect on reconsolidation of contextual drug-related memories.” It also highlights CBD’s potential to “attenuate contextual memories” from drug abuse, reducing the risk of relapse.
In simple words, the study concludes that CBD can help with addiction by altering memories linked to substance use.
The research team used cue exposure to tempt mice with a rewarding drug (morphine) and observed that taking CBD disrupted the cue. In a perfect world, this would mean that human cravings in addicts can be curbed with CBD too.
Long story short, the effects of CBD on memory may help addicts unlearn the habits of addiction. These habits give rise to cravings and pose a risk of relapse, long after withdrawal symptoms are gone. Some research also suggests that since CBD affects the memory in such a fashion, it may be able to help addicts in recovery by dissociating experiences with substance abuse.
What Else Does the Research Say About Taking CBD for Memory Enhancement?
Some studies suggest that even chronic low doses of THC can help to improve cognitive function — at least in animal models (9). As far as humans are concerned, there is growing data suggesting its positive effects on memory (as mentioned above).
Here’s a summary of the current research:
- A study from the Frontiers in pharmacology has found that CBD promotes neurogenesis — the growth and development of new cells in the brain. Neurogenesis prevents further cognitive deterioration. This specific study analyzed the effects of mice with induced Alzheimer’s condition prior to being treated with CBD. The CBD effectively reversed the cognitive impairments of the mice (10).
- A separate study indicates that an 8-month CBD treatment can prevent the development of social recognition memory deficits. Similar to the previous study, this one was conducted on mice in a controlled laboratory environment (11).
- According to a study from the American Journal of Psychiatry, CBD has a beneficial effect on schizophrenia. The authors claim that CBD’s activity is independent of dopamine receptor antagonism, which makes it a promising treatment for the condition (12).
- The aforementioned Australian review suggested similar health benefits of CBD. After covering 27 publications in peer-reviewed journals, researchers concluded that CBD enhances cognition in “preclinical models of cognitive impairment.” Cognitive impairment examined in the study included disorders such as schizophrenia, Alzheimer’s disease, meningitis, sepsis, malaria, hepatic encephalopathy, and brain ischemia (13).
That being said, we are still lacking clinical evidence on CBD for memory loss, and until more data is collected, we can only theorize about these effects and experiment with CBD on our own. The good news is that all animals share the same endocannabinoid system that responds to plant-based cannabinoids in a similar manner. This means that studies using animal models show a high degree of relevance, and positive results from such research usually give green light to human trials.
Can CBD Cause Short Term Memory Loss?
Perhaps one of the biggest stereotypes surrounding cannabis is that the long-term use of the plant may cause problems with short-term memory due to alleged brain damage.
Now that we’ve established CBD and THC are both antioxidants and neuroprotectants, you may be wondering whether those alleged problems are caused by some other properties of these cannabinoids.
The truth is, CBD doesn’t cause short term memory loss, and as the current evidence suggests, it can actually improve memory and focus, aiding people with cognitive disorders.
It’s the THC that May Cause Short Term Memory Loss… But Here’s The Catch!
When it comes to THC, this issue is less obvious. THC has been shown to cause short-term memory loss directly after use. The results came from adolescents and indicated problems with the ability to recall things. However, these results weren’t replicated in population studies, nor did they carry over to adult samples.
THC has a very similar structure to anandamide, which is one of the two major cannabinoids produced by the body. Anandamide comes from Sanskrit and means “ananda,” which translates to “bliss,” “joy,” and “happiness.”
Aren’t these the feelings you experience after hitting a vape pen with cannabis oil?
Anandamide also plays an important role in the formation and processing of memories. Anandamide deficits are associated with a faster onset of PTSD in people who have gone through trauma; it also causes a person to experience more severe flash-backs from traumatic events. THC happens to alleviate the symptoms of PTSD because it makes the memory more selective.
Now, when the user gets a bit too high for their tolerance, the brain takes it as if there was more anandamide than it actually needs to function on the optimal level. This is when the brain may become more selective than it should.
Ever found yourself in a situation where in the middle of telling a story, you lose a thought and need a few seconds to recall the message you’ve been trying to convey?
That’s the backfiring selectivity of your memory.
It’s not chronic and it stops once your body gets flushed from THC.
How Much CBD Should I Take?
There are no officially established standards for CBD oil when it comes to dosage. All people are different, so the optimal CBD dosage may vary between individuals who are going to take it for a memory boost.
Currently, the U.S. Food and Drug Administration (FDA) doesn’t regulate the safety and purity of dietary supplements. As you may guess, hemp-derived CBD products are categorized as supplements, so you also need to pay attention to the quality of your CBD oil. There are many products out there that contain less CBD than advertised.
But, when you have a high-quality product in your hand, looking for advice on the dosage, here’s one simple advice: start low and go slow.
Different studies recommend starting with 1–50 mg of CBD daily. While 1 mg is rather considered a microdose, most people start with 5–10 mg twice a day. For some people, CBD may provide fast relief, whereas others will need to give it some time to work in the endocannabinoid system. Still, if you don’t feel any difference after a week of testing your dose, increase it by another 5 mg, and monitor the results for next week.
Once you’ve found the amount of CBD that boosts your focus and memory, you can stick to it, as people don’t build a tolerance to CBD. The cannabinoid is even known to induce “reverse tolerance,” where users take less CBD over time due to feeling better.
Final Verdict: Does CBD Oil Really Improve Memory?
CBD oil may be a natural and safe alternative for those seeking help for memory loss. CBD has remarkable antioxidant and neuroprotective effects on the brain, and unlike traditional treatments, its use doesn’t raise safety concerns among patients.
Research from animal models and preliminary human studies has yielded promising results when it comes to the memory-boosting properties of CBD, although we’re still waiting for clinical trials to investigate its efficacy on a large scale. So far, we know that CBD reduces inflammation, curbs oxidative stress, and contributes to neurogenesis in the brain — all of which are essential for memory preservation.
If you’re thinking of adding CBD oil to your supplementation plan, make sure to consult with your doctor to avoid any adverse interactions that CBD may have with your current medication. A visit to a knowledgeable professional will also help you establish an effective dosage range for your individual situation.
Do you take CBD to boost memory? Let us know in the comments below!
- Ibeas Bih, Clementino et al. “Molecular Targets of Cannabidiol in Neurological Disorders.” Neurotherapeutics: the journal of the American Society for Experimental NeuroTherapeutics vol. 12,4 (2015): 699-730. doi:10.1007/s13311-015-0377-3
- Watt, Georgia, and Tim Karl. “In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer’s Disease.” Frontiers in pharmacology vol. 8 20. 3 Feb. 2017, doi:10.3389/fphar.2017.00020
- Panikashvili, D et al. “An endogenous cannabinoid (2-AG) is neuroprotective after brain injury.” Nature vol. 413,6855 (2001): 527-31. doi:10.1038/35097089
- Walter, Lisa, and Nephi Stella. “Cannabinoids and neuroinflammation.” British journal of pharmacology vol. 141,5 (2004): 775-85. doi:10.1038/sj.bjp.0705667
- Campbell, Christopher T et al. “Cannabinoids in Pediatrics.” The journal of pediatric pharmacology and therapeutics: JPPT: the official journal of PPAGvol. 22,3 (2017): 176-185. doi:10.5863/1551-6776-22.3.176
- Bériault, Maxime et al. “Comorbidity of ADHD and Anxiety Disorders in School-Age Children: Impact on Sleep and Response to a Cognitive-Behavioral Treatment.” Journal of attention disorders vol. 22,5 (2018): 414-424. doi:10.1177/1087054715605914
- Osborne, Ashleigh L et al. “A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia.” Neuroscience and biobehavioral reviews vol. 72 (2017): 310-324. doi:10.1016/j.neubiorev.2016.11.012
- de Carvalho, Cristiane Ribeiro, and Reinaldo Naoto Takahashi. “Cannabidiol disrupts the reconsolidation of contextual drug-associated memories in Wistar rats.” Addiction biology vol. 22,3 (2017): 742-751. doi:10.1111/adb.12366
- Bilkei-Gorzo, Andras et al. “A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice.” Nature medicine vol. 23,6 (2017): 782-787. doi:10.1038/nm.4311
- Watt, Georgia, and Tim Karl. Op. Cit.
- Cheng, David et al. “Long-term cannabidiol treatment prevent the development of social recognition memory deficits in Alzheimer’s disease transgenic mice.” Journal of Alzheimer’s disease: JAD vol. 42,4 (2014): 1383-96. doi:10.3233/JAD-140921
- McGuire, Philip et al. “Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial.” The American journal of psychiatry vol. 175,3 (2018): 225-231. doi:10.1176/appi.ajp.2017.17030325
- Osborne, Ashleigh L et al. Op. Cit.
Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.
Cannabis and memory loss: dude, where’s my CBD?
It isn’t often that science and pop culture overlap, but the two fields are in agreement when it comes to the familiar trope of the forgetful stoner.
A recent study published in Schizophrenia Bulletin is the latest to reveal the detrimental effects that cannabis can have on memory. The authors report that people dependent on the drug – both healthy individuals and patients with schizophrenia – show impairments in memory compared with healthy volunteers and non-smoking schizophrenia patients.
Even more striking, the cannabis-using groups had significant decreases in the volume of two brain areas that are important for processing rewards, learning and working memory – the thalamus and striatum – and these changes were linked to their memory problems. There was no evidence to connect cannabis use and schizophrenia – the authors simply compare the two groups. However, previous studies have found a higher prevalence of psychosis among regular cannabis smokers.
Reports of memory loss with long-term cannabis use are nothing new, and an influential paper published last year provided evidence that smoking marijuana has a deleterious effect on intelligence. In the investigation, the cognitive abilities of participants were tested several times over the course of 25 years. The researchers found that heavy cannabis users had significant decreases in intelligence and memory ability as they aged, not only compared with non-smokers, but also compared with their younger selves. Additionally, the earlier they started smoking pot, the bigger the cognitive decline.
Obviously these findings are worrying, especially given the recent spate of cannabis legalisations in states across the US and in countries such as Uruguay. However, before we all start worrying about the good people of Colorado and Washington, it might be helpful to look closer at what’s actually in the cannabis we’re smoking nowadays, and what ingredients are contributing to these cognitive deficits.
THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis and is what causes the subjective “high”. This includes changes in perceptual sensations, a feeling of contentedness and increased appetite. However, THC is also linked to many of the potential negative consequences of cannabis use, such as dependence, psychotic symptoms, and impaired memory and cognition.
Another important component, CBD (cannabidiol, which works by increasing natural cannabinoid levels in the brain) is associated with the calming, anti-anxiety effects of the drug. In addition, CBD is thought to protect against many of the potential negative effects of marijuana, including dependence, psychotic symptoms and cognitive impairments.
The THC concentration in cannabis has increased by as much as 12% over the past 30 years, making the drug much stronger than it used to be. At the same time, there has been a significant depletion of CBD, sometimes to levels as low as 0.1%. “Skunk”, as this new strain of high-THC/low-CBD marijuana is called, is flooding the illegal marijuana market, and it is this variety that is thought to be behind the rise in cannabis dependence diagnoses, links to schizophrenia, and cognitive deficits seen over the past decade.
The changing chemical make-up of cannabis appears to be partly accidental and partly deliberate. New strains are often bred to have higher levels of THC in them, increasing the drug’s potency. However, modern growing techniques have also affected these chemical levels. For example, illegal growers have turned to indoor marijuana farms to avoid detection. Growing cannabis locally in such farms also circumvents the need to import the drug, and guarantees a more reliable harvest. However, the 24-hour lighting used in these farms inadvertently reduces CBD levels in the plant. Thus, these new strains are not only bred for higher potency, with elevated THC content, they are also lacking the protection provided by CBD against the drug’s negative effects.
It should be noted that the majority of research into cognitive deficits and cannabis use has focused on heavy or dependent users, and there’s little evidence that occasional smokers show any of the problems mentioned above. But with the recent changes in drug policy, the chances are that more people will be smoking cannabis than ever before, and the more potent and more popular high-THC/low-CBD marijuana that is available today will increase their risk of dependence.
The recent legalisation of recreational and medicinal marijuana in parts of the US has the potential to reduce significantly the harms caused through incarceration or criminal records for minor drug-related offences. However, it also provides an opportunity to reduce the cognitive and psychiatric harms linked to cannabis use. With this shift in drug policy, it is now possible for states to monitor the commercial production of cannabis, regulating the levels of THC and CBD present in the drug. To facilitate this, they could force growers to use strains with higher levels of CBD, and revert to more old-fashioned farming methods that don’t use round-the-clock lighting.
These changes could help protect individuals from the damaging effects of the drug, prevent the development of dependence in new users, and maybe even help our favorite Hollywood stoners remember where they left their car.
CBD and Memory: Does CBD Affect Memory? – August 2022
CBD’s unique neurological health benefits could be the reason why some people see it as an appealing alternative remedy to help with memory loss. Results from previous scientific research and recent studies seem promising.
Several conditions can cause memory loss, especially in the elderly. Some conditions are treatable, while others, like Alzheimer’s, are not. Getting an immediate diagnosis and appropriate care is essential (6 ) .
For memory loss due to a traumatic brain injury (TBI) or caused by a condition, such as Alzheimer’s or dementia, the medications traditionally prescribed to treat symptoms include cholinesterase inhibitors and memantine. However, these medications can induce unwanted side effects, including nausea and headaches (7 ) .
CBD oil, meanwhile, does not produce those side effects. A study published in the British Journal of Pharmacology also demonstrated the anti-emetic (anti-nausea) effects of CBD, which is useful as a nausea and vomiting suppressant (8 ) .
Moreover, CBD’s anti-inflammatory and neuroprotective activities, as shown in a study published in PLoS One, make it an excellent potential alternative for improving brain function (9 ) .
Further longitudinal and robust studies are still required to derive high-quality evidence. However, results of scientific research conducted so far, suggesting CBD’s efficacy in improving cognition and helping with memory loss, are favorable.
Authors of a 2013 study examined the effects of cannabis use on memory function and found that cannabidiol (CBD) might possess anxiolytic (anti-anxiety) and antipsychotic effects (10 ) . Their data also showed that CBD did not impair cognition (11 ) .
The same authors reported that CBD might be protective of some aspects of memory function and might even reverse the deficits induced by tetrahydrocannabinol (THC), another primary cannabinoid (12 ) . THC is responsible for the intoxicating effects associated with the cannabis plant.
A 2017 study at the Australia’s University of Wollongong examined the effects of CBD on cognitive function in relevance to schizophrenia (13 ) .
The researchers of the said study found that CBD was effective in improving cognition for people with neurological disorders, neurodegenerative diseases, and neuro-inflammatory diseases, such as cerebral malaria and meningitis.
In another recent study , published in Frontiers in Pharmacology , researchers concluded that CBD might be a promising future avenue of research on neuroinflammation in response to traumatic brain injury (TBI) (14 ) . Learning and memory problems are among the most frequently reported symptoms following TBI (15 ) .
Memory loss caused by degenerative diseases, such as dementia and Alzheimer’s, is an area that CBD oil has been shown to have a potential positive impact.
In a 2017 study published in Frontiers in Pharmacology , CBD oil was shown to not only prevent the destruction of brain cells, but promote regrowth, or neurogenesis (16 ) .
The research mentioned above demonstrated CBD’s potential benefit for memory loss caused by conditions, such as dementia, Alzheimer’s, and traumatic brain injury, which may result in reduced cognitive function.
Other clinical trials have found that exposure to CBD for a prolonged period of eight months improves memory deficits related to social recognition (17 ) .
However, there may be individuals who may want to try CBD as a memory booster to help with forgetfulness.
Whether one is considering using CBD oil as a supplement to other medications for memory loss, or only as a memory aid, a consultation with a doctor before using CBD is essential.
CBD oil can interact with some medications, so caution is advised. Speak with a doctor who specializes in using CBD and other cannabis products in medical treatments.
How CBD Oil Works to Help with Memory Loss
Memory loss is often an initial sign of dementia and Alzheimer’s disease. Primarily, memory lapses may be mistaken for the typical forgetfulness that worsens as people grow old, or when they get stressed (18 ) .
CBD oil has been found to improve the health of those with dementia by lessening inflammation, reducing oxygenation, and stimulating and protecting the brain (19 ) .
The brain’s immune system has long been involved as a significant factor in the development of Alzheimer’s disease, particularly a specialized type of immune cell called microglia. The microglia cells help clear debris and toxic materials from the brain.
However, it appears that in Alzheimer’s, the immune cells do not function correctly or may even contribute directly to the disease process (20 ) .
The brain’s immune cells are also incapable of clearing blockages in dementia, and when situations like this occur, an inflammatory reaction is triggered. This inflammation has been shown to worsen symptoms of Alzheimer’s disease (21 ) .
CBD oil has been shown to reduce inflammation, with a 2017 study initially published in the Acta Biochimica et Biophysica Sinica Journal, noting that “CBD may be a promising candidate for Alzheimer’s disease therapy by inhibiting oxidative stress and neuroinflammation” (22 ) .
The inflammation that occurs in the brain due to Alzheimer’s disease is also called oxidation.As the oxidation process in the brain cells increase, functions such as memory decrease (23 ) .
However, CBD oil as antioxidant has been demonstrated to reduce this inflammatory effect, as indicated in a 2010 study on CBD oil and its effects on oxidative stress (24 ) .
The brain cell count in Alzheimer’s patients often undergoes a steady decline, reducing cognitive function and leaving destroyed pathways behind (25 ) .
CBD oil has been demonstrated in numerous studies to not only exhibit neuroprotective, anti-inflammatory and antioxidant properties but also promote neurogenesis, a process by which new neurons are formed in the brain (26 ) .
Newborn neurons at different maturation stages might make distinct contributions to learning and memory, according to a study published in Nature Reviews Neuroscience (27 ) .
The Pros and Cons of CBD Oil for Memory Loss
- CBD “is generally well tolerated with a good safety profile,” as the World Health Organization (WHO) states in a critical review (28 ) .
- CBD’s efficacy as a potential to help with memory loss has been shown in the numerous studies stated above.
- Studies are too limited to determine whether or not CBD is an effective treatment for conditions other than the ones approved by the U.S. Food and Drug Administration (FDA).
- As with the use of any natural chemical compound, there are risks involved in using CBD. According to the Mayo Clinic, possible side effects include drowsiness, dry mouth, diarrhea, fatigue, and reduced appetite (29 ) .
- CBD has been shown to alter how the body metabolizes certain medications, as a 2017 research published in the Cannabis and Cannabinoid Research journal reveals (30 ) .
Thus, consult with a doctor before taking CBD, especially when combining it with other prescription pharmaceuticals for memory loss.
- The lack of regulation makes it difficult to determine whether the CBD gummies, tinctures, patches, balms, and gelcaps contain what the product label claims.
A 2107 review published in the Journal of the American Medical Association revealed labeling inaccuracies among CBD products. Some products had less CBD than stated, while others had more (31 ) .
Speak with a physician experienced with cannabis use before starting a CBD regimen.
How CBD Oil Compares to Alternative Treatments that Help with Memory Loss
Some plant extracts, like Ginkgo biloba, lemon balm, and lavender, are often used as alternative treatments to help with symptoms of dementia and Alzheimer’s disease (32 ) .
Ginkgo biloba extract, derived from the leaves of the Ginkgo biloba tree, is often hailed as a memory aid.
However, according to a Mayo Clinic article, some studies have shown that the use of the extract provided little improvements in cognitive function for people.
Thus, most experts feel that the extract has not lived up to its early promise and do not recommend its use as a memory aid (33 ) .
Published in Nutrients , a 2014 study on lemon balm’s anti-anxiety effects showed that it might also help improve cognition and mood (34 ) .
Likewise, CBD might also help reduce anxiety, as results of a study published in the Journal of Psychopharmacology suggested (35 ) .
In a study published in the Journal of Korean Academy of Nursing in 2017, lavender oil was shown to reduce occurrences of aggressive behavior in dementia (36 ) .
Results of the study also demonstrated that a lavender aromatherapy hand massage program is effective on emotions and aggressive behavior of elderly with dementia of the Alzheimer’s type.
However, further research is required. Although massage therapies show promise, studies have not been longitudinal and rigorous enough to provide high-quality evidence.
Meanwhile, like the plant extracts mentioned above, CBD oil is a natural cannabis extract that has been shown in studies to help with memory loss. CBD in the form of tincture can also be used in aromatherapy and massage.
Using CBD oil may be an excellent alternative remedy to symptoms of disorders that affect memory, such as dementia and Alzheimer’s disease. As indicated in studies previously discussed, CBD’s neuroprotective, anti-inflammatory, and anti-anxiety properties may help protect the brain and improve cognition.
How to Choose the Right CBD for Memory Loss
Finding the CBD product that suits one’s needs and preference may require a little experimentation and some time. What works best for an individual may not work for someone else.
Still, regardless of the form of CBD product one chooses, he or she must employ careful consideration in choosing the best CBD oil that is right for him or her.
The following factors are essential to ensure the safety and reliability of the CBD products purchased:
- Research on the exact legal status and stipulations applicable to CBD in the area where it would be purchased and used.
- Purchase only from legitimate and reliable big brands. The majority of companies that manufacture the best CBD oil products grow their hemp from their farm, or they purchase from licensed hemp producers.
- When buying from an online store, do some research on product reviews first. When buying from a physical store or dispensary, check whether the store is authorized by the government to sell CBD.
- One important thing to look for in CBD products is certification codes. Several certification authorities approve certain products only after some thorough screening tests.
- Compare company claims about their products’ potency with that of the third-party lab reports.
Because of the unclear regulations in the United States and some problems with online product labeling, the authors of a Mayo Clinic article recommended the use of imported products from Europe (37 ) .
The same authors explained that Europe, aside from having a more established regulatory system for hemp, has more stringent requirements for low THC levels at less than 0.2% dry weight compared with the US requirement of less than 0.3% dry weight.
Still, consulting with a trusted medical professional experienced in CBD use is ideal before purchasing any CBD product.
CBD Dosage for Memory Loss
There is no standard for CBD oil when it comes to dosage. Because all people are different, there can be variations in the amount needed to find relief or improve memory.
CBD is mostly marketed as a supplement, not a medication. Currently, the U.S. Food and Drug Administration (FDA) does not regulate the safety and purity of dietary supplements.
Thus, CBD consumers cannot know for sure that the product they buy has active ingredients at the dose listed on the label. The CBD product may also contain other unknown elements.
Peter Grinspoon, MD, said in an article posted in Harvard Health, that they also do not know the most effective therapeutic dose of CBD for any particular medical condition (38 ) .
How to Take CBD Oil for Memory Loss (and Why)
The delivery method an individual chooses for taking CBD depends on one’s preference and lifestyle.
CBD Oil Capsules and Edibles
CBD oil capsules and edibles, such as brownies, gummies, and lozenges, are a convenient and straightforward way to take CBD oil, especially for beginners. They may be added to a current medication or vitamin regimen, or they may be taken with food and beverages.
This format is easy to include in one’s routine, and the dose is consistent. These advantages are helpful especially when memory is an ongoing concern.
Depending on one’s metabolism, the effects can last between 6 and 12 hours. However, the effects of the CBD oil could take at least 20 minutes to an hour to appear. Thus, CBD oil capsules and edibles do not provide immediate relief.
CBD Oil Tinctures or Drops
CBD oil tinctures or drops are a practical option for those who seek fast results and maximum dosage control.
Tinctures and drops are administered sublingually (under the tongue), through which the CBD oil is absorbed directly into the bloodstream.
Sublingual application allows for results to be experienced within 30 to 60 minutes after its use, and the effects can be felt for 4 to 6 hours.
Since tinctures and drops are convenient and easy to store and travel with, they can be effortlessly administered when needed.
However, one significant drawback to CBD oil tinctures and drops is the taste as not everyone appreciates the natural, earthy, and sometimes bitter flavor of hemp.
CBD Oil Vapes
CBD oil vapes are one of the accelerated ways to get CBD into the body since it enters the bloodstream through the lungs, without going through the digestive system.
When vaping CBD oil, effects can be felt in minutes. However, the effects last only for 30 minutes to an hour or two. Thus, it may not be the most effective option for improving memory.
Also, with vaping, it is difficult to determine precisely how much CBD is in each draw. Although labels for CBD oil vape products usually indicate the amount per inhale, everyone’s inhale is unique. Thus, getting the dose right requires a bit of experimentation at first.
A Closer Look at CBD
Cannabis sativa L. (Cannabaceae) is a type of cannabis that is one of the most recognized ancient plants. Sativa is Latin for “useful”, and it is a term that is commonly used in plant names.
Cannabis oil products include hemp oil and marijuana concentrates.
A hemp plant and a marijuana plant both belong to the plant genus cannabis. Cannabis is classified as a Schedule I drug in the United States but is legally accepted in 16 states and the District of Columbia for therapeutic purposes.
Cannabidiol (CBD) is an active ingredient in cannabis derived from the hemp plant and is commonly used to produce CBD hemp oil supplements.
CBD is non-intoxicating and non-addictive. CBD extracted from hemp is legal under U.S. federal law (39 ) .
One of the primary differences between CBD and THC lies in how they affect an individual who consumes them.
Although CBD and THC are similar in chemical structure, they do not share the same psychoactive effects. THC binds with the cannabinoid 1 or CB1 receptors in the brain and produces a sense of euphoria. THC is the cannabinoid that is mostly associated with marijuana or weed
CBD, however, binds inadequately to CB1 receptors. CBD can even disrupt the binding of THC and suppress its psychoactive effect, as researchers of a 2018 study published in the Neuropsychopharmacology Journal suggest. CBD, a non-psychoactive compound, does not induce the “high” associated with THC (40 ) .
THC and CBD are both found in the flowers, seeds, and stalks of both hemp and marijuana. Both cannabinoids naturally exist in cannabis plants in a broad range of proportions.
THC is most abundant in marijuana, while CBD is found in substantial quantities in hemp. The CBD oil ingredient that is found in most CBD oil products is extracted from the hemp plant.
CBD and the Immune System
The endocannabinoid system is interrelated with the immune system. To comprehend how CBD affects the body’s immune system, one must understand how the endocannabinoid system (ECS) works.
A 2008 study published in the Pharmacological Reviews Journal explored the endocannabinoid system and its regulatory functions in health and diseas e (41 ) .
The ECS is found in the central and peripheral nervous systems. It is a network of cannabinoids and CB1 and CB2 receptors, and it regulates most functions in the human body.
The ECS also acts as an immuno-cannabinoid modulator as it gathers and interprets signals from cannabinoids.
The body is capable of producing some cannabinoids on its own, which are called endocannabinoids. The ECS helps to manage functions such as immune-system responses, sleep, and pain, influencing a person’s physiology, mood and everyday experience.
Cannabinoids and terpenes work together to develop a cannabis strain’s distinctive flavor, resulting in a phenomenon known as the entourage effect.
Some neurotransmitters in the brain provide instructions for the body’s immune system and signal it when to activate its line of defense, where to engage it, and how strongly to involve it. Others are responsible for mood, emotions, and cognition.
Dementia, Alzheimer’s, and MIC
Disorders categorized under the general term “dementia” are caused by abnormal brain changes. These changes trigger a decline in thinking skills, also known as cognitive abilities, severe enough to impair daily life and independent function. Alzheimer’s is the most common cause of dementia and accounts for 60 to 80 percent of cases (42 ) .
Mild cognitive impairment leads to changes in cognition serious enough to be observed by other people but do not impact the individual’s ability to carry out everyday activities.
People living with MCI, especially MCI involving memory problems, are more likely to develop Alzheimer’s disease or other dementias than people without MCI.
A medical workup for MCI includes an assessment of one’s mental health using tests designed to evaluate memory, planning, judgment, and other critical thinking skills (43 ) .
For those suffering from memory loss, CBD oil may be an all-natural alternative to traditional medications or increasing concerns about impaired functioning.
Research into this all-natural compound from cannabis is still in the early stages. Even so, studies suggest that CBD has antioxidant, anti-inflammation, and analgesic properties, with the first two being crucial for memory preservation.
Still, before taking CBD, people are advised to consult with their doctor to avoid any adverse interactions that CBD may have with their current medications.
For more information on memory loss and forgetfulness, visit the National Institutes of Health ( NIH ) website (44 ) .
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Table of Contents
Nervous & Sensory System
Dr. Kimberly Langdon, MD
Kimberly Langdon, MD is a retired, board-certified obstetrician/gynecologist with 19-years of clinical experience. She graduated from The Ohio State University College of Medicine, earning Honors in many rotations. She then completed her OB/GYN residency program at The Ohio State University.
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